در موش سفيد كوچك آزمايشگاهي مبتلا به فرم مزمن بيماري RH بروزتوكسوپلاسموزيس حاد به دنبال آلودگي باسويه

Acute Toxoplasmosis Following Re-infection with RH Strain in Mice with the Chronic for of the Disease

Chronic toxoplasmosis often is associated with a protective immunity against re-infection. The object of this study was to determine the efficacy of immunity against reinfection with the RH strain of Toxoplasma. Mice with chronic toxoplasmosis were injected through IP with the RH strain. All died 3-5 days after infection. This result indicates that the immune responses in chronic infection with toxoplasma can not protect this animal against acute toxoplasmosis with the RH strain. If this situation applies to in human toxoplasmosis, infection of pregnant women is dangerov because if a pregnant women is infected with a different toxoplasma strain prior to pregnancy, the fetus may be infected with congenital toxoplasmosis.