اثر رژيم غذايي حاوي كاسني يا لوبيا بر كنترل قند خون در موش صحرايي ديابتي

Effect of Kidney Bean and Chicory Diets on Control of Blood Sugar in Diabetic Rats

The effects of herbal remedies is gaining increasing importance, due to their minimal side effects and their co-existence with complex compounds in nature. On the other hand, the importance of appropriate foods in the treatment of the patient with diabetes mellitus is why we chose two of the most frequently used medicinal herbs Phaseolus Vulgaris (kidney bean) and chicory to investigate the effect of these herbal consumption on blood sugar in diabetic rats. The adult male rats were divided into eleven groups. Diabetes was induced experimentally by aloxan monohydrate (150 mg/kg sc) injection. After observation of diabetic signs, the animals were divided into eleven groups: The control group was fed a standard diet, and the ten other groups (test groups). Five of the test groups were treated for 4 weeks, with 10%, 20%, 30%, 40%, and 50% chicory and the other five with 10-50% kidney bean diets. Four weeks after induction of diabetes, blood glucose was measured via glucometer, in all groups. According to the results blood glucose was decreased significantly in the rats fed diets containing chicoryina in a dose-dependent manner and also in the 20% kidney bean group. The 30% and 50% chicory diets caused a reduction of 22.6% and 44.3% in blood glucose respectively. The 20% kidney bean diet caused a reduction of 17.2% in blood glucose, and no signifcant decrease in blood glucose was observed in the other kidney bean diet groups. These results showed that, ingestion of chicory was more effective than kidney beans in diabetic rat, and the effect of chicory diets are dose-dependent. These diets may be investigated in treatment of IDDM in humans.