عدم تطابق وزن دوقلوها و خطر زايمان زودرس

Twin birth weight discordance and risk of pre-term birth

Background and Objectives: The association between discordant growth and the complication of twin prgnancy has been recognized for more than 30years. Recent publications have presented evidence that 30% or even 40% discordancere presents the threshold for significante. Our purpose was to define twin growth discordance on the basis of perinatal outcome and other factors like mathernal age pariety and systemic disease. Materials and Methods: Twins delivered at age more than 32 weekʹs gestation between 1998-2000 at Deziani hospital Gorgan was identified. Birth weight, pre-term birth, mathernal age pariety and systemic disease and sex of twins recorded. Discordance was calculated as: 100 *Larger BW-Samller BW/Larger BW Results: The mean discordance for 435 twins was 8.18±6.79. 96.4% of pre-term birth associated with discordance >_20%. 10.6% of mathers had a systemic disease and mean discordance in twins term and pre-term of normal mothers was 5.8±4.5, 7.9±6.3 and in systemic disease was 9±9.2, 11.1±8.8 (P<_0.008). There was no diffrences in pariety age and sex. Conclusion: Twin birth weight discordance had now clearly been demonstratd to be a risk factor for pre-term birth. The effect was found particularly with discordances ?20% after 32 weekʹs gestation.