مقايسه اثر التيام بخش عصاره بره موم (Propolis) و پماد فني توئين سديم بر زخم ماهي كوي (Cyprinus carpio haematopterus)

The Comparision of Therapeutic Effect of Propolis Extract and Phenytoin on the Wound of Koifish Cyprinus carpio haematopterus

در اين مطالعه اثر بهبود بخشي عصاره اتانولي بره موم عسل بر زخم جراحي ماهي كوي به عنوان يك ماده طبيعي رزيني داراي خواص زيستي متعدد ارزيابي شد. سه ماهي از هر يك از 4 تانك جداگانه از كل 36 ماهي سازگار شده به صورت تصادفي انتخاب و بعد از زخم زدن و بخيه، مورد درمان با تيمارهاي مختلف قرار گرفتند. روي زخمهاي ايجاد شده در بدن ماهيان در گروههاي آزمايشي به مدت ده روز سه تيمار دارويي با عصاره هاي 1% و2% بره موم و نيز پماد بهبود زخم فنوتوئين سديم و نيز با وازلين تنها براي گروه شاهد، به كارگرفته شدند. تحليل نتايج با استفاده از آمار توصيفي انجام شد. در ميان گروهها موثرترين تيمار از علائم بهبود زخم از بره موم 2% بروز نمود، هر چند عصاره 1% بره موم و پماد فنوتوئين سديم نيز از نظر علائم (ترميم پوست، خونريزي داخلي، ادم ، التهابات، ضايعات نكروتيك و چسبندگي بافتها) نتايج بهبود را نشان دادند. ماهيان گروه شاهد در زخمهايشان علائم باقي مانده اي از عفونت و صدمات پوستي را علاوه بر چسبندگي بافتها به همراه داشتند.

This study aimed to assess the healing effect of ethanolic extract of Propolis as a natural resinous substance, possessing various biological properties, on the surgically experimental ulcer of Koi fish. Thirty-six Koi fish were randomly divided into 4 equal experimental groups for initial adaptation. Then three limited surgically cut wounded fish from the every group were cured under desired experimental cares, as three treatment groups (two doses of 10 and 20 mg/gr of the Propolis Ethanolic Extract (EEP) and Phenitoean Sodium %1) and one control (only Vaseline). The experimental doses of EEP and Phenitoean were respectively used as the Vaseline base made and the standard commercial Phenitoean Soudium ointments, one time a day for 10 days, as well Vaseline treatment (for the control group). The data were analyzed, using descriptive statistics methods. The results showed that dose of 2% of EEP were the most effective in the treatment of experimental surgically wounds. The signs of the wound were more healed in the 2% group, however the external and internal health effects were observed for the other dose of EEP (%1) and the standard Phenitoean (with criterion of cured skins quality signs, internal haemoragies, observed edema, inflammation and tissue adhesions) after 10 days. The control group wounds had retained the most signs of infection and skin damages, as well the internal viscose.