Title List مقالات لاتين Discovering filter keywords for company name disambiguation in twitter Discrete anchoring: Bulk-substrate coupling in lattice models

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Discovering filter keywords for company name disambiguation in twitter

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Discovering Frequent Itemset with Maximum Time-Window on Temporal Transaction Database using Variable Neighborhood Search

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Discovering frequent itemsets over transactional data streams through an efficient and stable approximate approach

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Discovering fuzzy inter- and intra-object associations

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Discovering gene–gene relations from sequential sentence patterns in biomedical literature

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Discovering groups of key potential customers in social networks: A multi-objective optimization model

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Discovering hidden pricing power

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Discovering hidden structure in factored MDPs Original Research Article

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Discovering hierarchical object models from captioned images

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Discovering high quality answers in community question answering archives using a hierarchy of classifiers

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Discovering how end-user programmers and their communities use public repositories: A study on Yahoo! Pipes

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Discovering how end-user programmers and their communities use public repositories: A study on Yahoo! Pipes

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Discovering human immunodeficiency virus mutational pathways using temporal Bayesian networks

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DISCOVERING IMPERCEPTIBLE ASSOCIATIONS BASED ON INTERESTINGNESS: A UTILITY-ORIENTED DATA MINING APPROACH

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Discovering Industrial Ecology — An Executive Briefing and Sourcebook: Ernest A. Lowe, John L. Warren and Stephen R. Moran; Battelle Press, Columbus, Ohio, ISBN 1-57477-034-9.

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Discovering influencers for marketing in the blogosphere

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Discovering Influencers for Spreading in Weighted Networks

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Discovering influential cases in linear regression with MINITAB: Peeking into multidimensions with a MINITAB macro

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Discovering Information Use in Agricultural Economics: A Citation Study

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Discovering interest groups for marketing in virtual communities: An integrated approach

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Discovering Interesting Association Rules in the Web Log Usage Data

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Discovering Iranian EFL Teachers’ Metalinguistic Knowledge: The Role of Academic Degree and Teaching Experience in Focus

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Discovering knowledge from noisy databases using genetic programming

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Discovering knowledge of hemodialysis (HD) quality using granularity-based rough set theory

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Discovering knowledge of medical quality in total hip arthroplasty (THA)

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Discovering latent topical structure by second-order similarity analysis

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Discovering Learner Styles in Adaptive e-Learning Hypermedia Systems

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Discovering long lifetime routes in mobile ad hoc networks

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Discovering Maximal Generalized Decision Rules Through Horizontal and Vertical Data Reduction

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Discovering meaningful information from large amounts of environment and health data to reduce uncertainties in formulating environmental policies

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Discovering medical resource utilization in total knee arthroplasty (TKA) using rule-based method

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Discovering metabolites of post-harvest fungicides in citrus with liquid chromatography/time-of-flight mass spectrometry and ion trap tandem mass spectrometry

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Discovering metamodels’ quality-of-fit for simulation via graphical techniques

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Discovering metric temporal constraint networks on temporal databases

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Discovering mirror particles at the Large Hadron Collider and the implied cold universe

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Discovering missing heritability and early risk prediction for type 2 diabetes: a new perspective for genome-wide association study analysis with the Nurses’ Health Study and the Health Professionals’ Follow-Up Study

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Discovering mobile users’ moving behaviors in wireless networks

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Discovering multi-label temporal patterns in sequence databases

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Discovering nature, rediscovering the self: natural historians and the landscapes of Argentina

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Discovering network behind infectious disease outbreak

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Discovering new genes with advanced homology detection

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Discovering new inhibitors of bacterial glucosamine-6P synthase (GlmS) by docking simulations

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Discovering New MAP Kinase Inhibitors

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Discovering New V-Type Asteroids in the Vicinity of 4 Vesta

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Discovering non-Abelian weak couplings and an anomalous magnetic dipole moment of the W± at LEP 2

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Discovering novel brain lipids by liquid chromatography/tandem mass spectrometry

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Discovering novel chemical inhibitors of human cyclophilin A: Virtual screening, synthesis, and bioassay Original Research Article

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Discovering nursing excellence through appreciative inquiry

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Discovering Nutrition: Editor: Timothy Carr. Blackwell Publishing, Oxford, UK, 2003; vii+214 pages, paperback, ISBN0632045647; £20.95;/US$24.95;

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Discovering of Asbestos Fibers and Corn Starch in Talc Material of Baby Powder Samples from Different Markets in Benghazi City

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Discovering order

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DISCOVERING PATHWAYS OF SARCOPENIA IN OLDER ADULTS: A ROLE FOR INSULIN RESISTANCE ON MITOCHONDRIA DYSFUNCTION

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Discovering patterns in categorical time series using IFS

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Discovering patterns of missing data in survey databases: An application of rough sets

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Discovering Popular Clicks Pattern of Teen Users for Query Recommendation

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Discovering Popular Clicks' Pattern of Teen Users for Query Recommendation

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Discovering power laws in computer programs

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Discovering predictive rules of chemistry from property landscapes

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Discovering price-load relationships in Californiaʹs electricity market

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Discovering process models from event multiset

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Discovering reliable protein interactions from high-throughput experimental data using network topology

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Discovering repetitive patterns in facade images using a RANSAC-style algorithm

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Discovering Research Topics from Medical Librarianship and Information Using Text Mining

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Discovering Reservoir Operating Rules by a Rough Set Approach

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Discovering rules for water dem، prediction: An enhanced rough-set approach

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Discovering selective agonists of endothelial target for acetylcholine (ETA) via diversity-guided pharmacophore simplification and simulation

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Discovering Semantic Aspects of Socially Constructed Knowledge Hierarchy to Boost the Relevance of Web Searching

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Discovering semantic associations among Web services based on the qualitative probabilistic network

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Discovering Semantic Web services using SPARQL and intelligent agents

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Discovering shared conceptualizations in folksonomies

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Discovering simple rules in complex data: A meta-learning algorithm and some surprising musical discoveries Original Research Article

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Discovering simulation models

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Discovering Small Molecules that Promote Cardiomyocyte Generation by Modulating Wnt Signaling Original Research Article

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Discovering spawning ground of Hilsa shad (Tenualosa ilisha) in the coastal waters of Bangladesh

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Discovering spawning ground of Hilsa shad (Tenualosa ilisha) in the coastal waters of Bangladesh

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Discovering syntactic deep structure via Bayesian statistics

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Discovering Term Occurrence Structure in Text

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Discovering the ‘international’ in accounting and finance

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Discovering the acoustic correlates of phonological contrasts

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Discovering the aetiology of heart failure, one link in the chain to improved survival

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Discovering the algebraic structure on the metric injective envelope of a real Banach space

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Discovering the barriers to spread the usage of peripherally inserted central venous catheters in the neonatal intensive care units: A qualitative research

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Discovering the chemical reactivity of the molecular oxonitride [{Ti(η5-C5Me5)(μ-O)}3(μ3-N)]

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Discovering the Clinical Knowledge about Breast Cancer Diagnosis Using Rule-Based Machine Learning Algorithms

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Discovering the Effect of Organizational Ethical Climate on Knowledge Management

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Discovering the effects of feedback on control systems: informative and interesting numerical exercises

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Discovering the Ending in the Beginning

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Discovering the fullerenes

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Discovering the gap between Web site designersʹ expectations and usersʹ behavior

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Discovering the hotel selection preferences of Hong Kong inbound travelers using the Choquet Integral

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Discovering the importance of lateral CO2 transport from a temperate spruce forest

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Discovering the influential users oriented to viral marketing based on online social networks

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Discovering the leader within: Running small groups successfully : by Randy Fujishin. San Francisco: Acada Books, 1997. 176p. $15.95 (paper). ISBN 09655029-10. LC 96-79626

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Discovering the linear writing order of a two-dimensional ancient hieroglyphic script Original Research Article

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Discovering the mercantile city in South Asia: the example of early nineteenth-century Calcutta

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Discovering the Pattern of Interactions in Online Discussions Using the Social Network Analysis Principle

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Discovering the potential of bioactive compounds from 𝑐𝑢𝑟𝑐𝑢𝑚𝑎 𝑎𝑒𝑟𝑢𝑔𝑖𝑛𝑜𝑠𝑎 as anti-ovarian cancer agent through in silico approach targeting TNFα

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Discovering the potential of cloud computing in accelerating the search for curing serious illnesses

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DISCOVERING THE RELATIONSHIP BETWEEN CONTEXT AND ALLOPHONES IN A SECOND LANGUAGE: Evidence for Distribution-Based Learning

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Discovering the role of mitochondria in the iron deficiency-induced metabolic responses of plants Review Article

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Discovering the secrets of the sun By R. Kippenhahn: Wiley, 1994, 262 pp. ISBN 0 471 94363 0

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Discovering the Self in Islam: Self-Striving, Self-Regard, and Self-Neglect

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Discovering the Semantics of User Keywords

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Discovering the Unknown Landscape: A History of America’s Wetlands by Ann Vileisis, Island Press, Washington, D.C. and Covelo, CA, 1997

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Discovering the Variances in Language and Culture: A Comparison of Chinese and English Language Advertisements

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Discovering theorems in game theory: Two-person games with unique pure Nash equilibrium payoffs Original Research Article

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Discovering time-interval sequential patterns in sequence databases

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Discovering transthyretin amyloid fibril inhibitors by limited screening Original Research Article

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Discovering Users` Access Patterns for Web Usage Mining from Web Log Files

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Discovering words in the continuous speech stream: the role of prosody

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DISCOVERY 2010: Spatial and temporal variability in a dynamic polar ecosystem

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Discovery and activity of (1R,4S,6R)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-2-methyl-2-azabicyclo[2.2.2]octane-6-carboxamide (3, RY764), a potent and selective melanocortin subt

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Discovery and analysis of e-mail-driven business processes

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Discovery and antibacterial activity of lucensimycin C from Streptomyces lucensis

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Discovery and application of a new enzyme N-acylamino acid racemase

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Discovery and application of iminotriphenylphosphorane as a formal aromatic primary amine protecting group

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Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSP

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Discovery and biological characterization of capromorelin analogues with extended half-lives

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Discovery and biological evaluation of adamantyl amide 11β-HSD1 inhibitors

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Discovery and biological evaluation of benzo[a]carbazole-based small molecule agonists of the thrombopoietin (Tpo) receptor

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Discovery and biological evaluation of novel α-glucosidase inhibitors with in vivo antidiabetic effect

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Discovery and Biological Evaluation of Potent Dual ErbB-2/EGFR Tyrosine Kinase Inhibitors: 6-Thiazolylquinazolines

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Discovery and biological profile of 4-(1-aryltriazol-4-yl)-tetrahydropyridines as an orally active new class of metabotropic glutamate receptor 1 antagonist Original Research Article

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Discovery and characteristics of the Kuiper belt binary 2003QY90

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Discovery and characterization of [3H]8-OH-DPAT binding to HeLaS3 cells

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Discovery and Characterization of 2-Aminobenzimidazole Derivatives as Selective NOD1 Inhibitors

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Discovery and Characterization of 2-Anilino-4- (Thiazol-5-yl)Pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents Original Research Article

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Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site Original Research Article

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Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain Original Research Article

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Discovery and Characterization of a Linear Cyclotide from Viola odorata: Implications for the Processing of Circular Proteins

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Discovery and characterization of a novel splice variant of the GM-CSF receptor α subunit

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Discovery and characterization of a selective, nonpeptidyl thrombopoietin receptor agonist

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Discovery and characterization of endo-xylanase and β-xylosidase from a highly xylanolytic bacterium in the hindgut of Holotrichia parallela larvae

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Discovery and characterization of Plum pox virus isolates in Montenegro

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Discovery and Characterization of the Laulimalide-Microtubule Binding Mode by Mass Shift Perturbation Mapping Original Research Article

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Discovery and characterization of the potent, selective and orally bioavailable MMP inhibitor ABT-770

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Discovery and characterization of two types of liver-expressed antimicrobial peptide 2 (LEAP-2) genes in rainbow trout

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Discovery and characterization of two types of liver-expressed antimicrobial peptide 2 (LEAP-2) genes in rainbow trout

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Discovery and communication of important marketing findings: Evidence and proposals

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Discovery and cross-section measurement of 58 new fission products in projectile-fission of 750 · A MeV 238U

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Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase

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Discovery and development of antidepressants: a perspective from a pharmaceutical discovery company

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Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters

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Discovery and development of lamotrigine for bipolar disorder: A story of serendipity, clinical observations, risk taking, and persistence

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Discovery and development of metallocene-based polyolefins with special properties

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Discovery and development of neuronal nitric oxide synthase inhibitors

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Discovery and development of sesquiterpenoid derived hydroxymethylacylfulvene: a new anticancer drug Original Research Article

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Discovery and DNA analysis of the invasive freshwater mussel Sinanodonta lauta (Unionidae) in south Iran

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Discovery and evaluation of 3-(5-Thien-3-ylpyridin-3-yl)-1H-indoles as a novel class of KDR kinase inhibitors

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Discovery and evaluation of N-(triazin-1,3,5-yl) phenylalanine derivatives as VLA-4 integrin antagonists

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Discovery and evaluation of piperidinyl carboxylic acid derivatives as potent α4β1 integrin antagonists

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Discovery and evaluation of potent, cysteine-based α4β1 integrin antagonists

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Discovery and evaluation of potent, tyrosine-based α4β1 integrin antagonists

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Discovery and follow-up simulations for small Earth-crossing asteroids

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Discovery and identification of new non-ATP competitive FGFR1 inhibitors with therapeutic potential on non-small-cell lung cancer

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Discovery and implication of P21/n crystal structure on a nano-scale in single jadeite crystals

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Discovery and in vitro evaluation of potent kinase inhibitors: Pyrido[1′,2′:1,5]pyrazolo[3,4-d]pyrimidines

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Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles

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Discovery and in vitro/in vivo studies of tetrazole derivatives as Kv1.5 blockers

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Discovery and initial development of a novel class of antibacterials: Inhibitors of Staphylococcus aureus transcription/translation

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Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56Lck

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Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R)

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Discovery and Initial SAR of Arylsulfonylpiperazine Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1)

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Discovery and initial SAR of imidazoquinoxalines as inhibitors of the Src-family kinase p56Lck

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Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4

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Discovery and initial structure–Activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists

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Discovery and integration of univariate patterns from daily individual organ-failure scores for intensive care mortality prediction

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Discovery and investigation of a novel class of thiophene-derived antagonists of the human glucagon receptor

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Discovery and molecular cloning of piscidin-5-like gene from the large yellow croaker (Larimichthys crocea)

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Discovery and optimisation of potent, selective, ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase

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Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR)

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Discovery and optimization of 2-aryl oxazolo-pyrimidines as adenosine kinase inhibitors using liquid phase parallel synthesis

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Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide

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Discovery and optimization of a novel series of liver X receptor-α agonists

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Discovery and optimization of a series of quinazolinone-derived antagonists of CXCR3

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Discovery and optimization of indole pyrrolothiazole paf antagonists

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Discovery and optimization of nonpeptide HIV-1 protease inhibitors Original Research Article

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Discovery and optimization of novel, non-steroidal glucocorticoid receptor modulators

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Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase

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Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant α4β2 nicotinic acetylcholine receptor potentiators

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Discovery and parallel synthesis of a new class of cathepsin k inhibitors

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Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor

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Discovery and preliminary evaluation of 5-(4-phenylbenzyl)oxazole-4-carboxamides as prostacyclin receptor antagonists

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Discovery and preliminary structure–activity relationship studies of novel benzotriazine based compounds as Src inhibitors

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Discovery and SAR development of 2-(phenylamino) imidazolines as postacyclin receptor antagonists

186

Discovery and SAR development of thienopyridones: A class of small molecule AMPK activators

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Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents

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Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer Original Research Article

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Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors

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Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors

191

Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease

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Discovery and SAR of 4-amino-2-biarylbutylurea MCH 1 receptor antagonists through solid-phase parallel synthesis

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Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis

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Discovery and SAR of diarylsulfide cyclopropylamide LFA-1/ICAM-1 interaction antagonists

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Discovery and SAR of hydrazide antagonists of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor type 1 (PAC1-R)

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Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind β-secretase in a N-terminal 10s-loop down conformation

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Discovery and SAR of new benzazepines as potent and selective 5-HT2C receptor agonists for the treatment of obesity

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Discovery and SAR of novel [ and ]Naphthyridines as potent inhibitors of spleen tyrosine kinase (SYK)

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Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)

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Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors

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Discovery and SAR of Org 24598—A Selective Glycine Uptake Inhibitor

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Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers

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Discovery and SAR of potent, orally available and brain-penetrable 5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen- and 4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen derivatives as neuropeptide Y Y5 receptor antagonists

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Discovery and SAR of trisubstituted thiazolidinones as CCR4 antagonists

205

Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors

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Discovery and SAR studies of novel GlyT1 inhibitors

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Discovery and SAR study of novel dihydroquinoline containing glucocorticoid receptor ligands

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Discovery and SAR study of novel dihydroquinoline-containing glucocorticoid receptor agonists

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Discovery and Significance of Eclogite-Granitoid Belts in Northwest China

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Discovery and stereoselective synthesis of the novel isochroman neurokinin-1 receptor antagonist ‘CJ-17,493’ Original Research Article

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Discovery and Structural Characterization of a New Inhibitor Series of HIV-1 Nucleocapsid Function: NMR Solution Structure Determination of a Ternary Complex Involving a 2:1 Inhibitor/NC Stoichiometry

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Discovery and structure–activity relationship analysis of Staphylococcus aureus sortase A inhibitors Original Research Article

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Discovery and structure–activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducers

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Discovery and structure–activity relationship of coumarin derivatives as TNF-α inhibitors

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Discovery and structure–activity relationship of N-phenyl-1H-pyrazolo[3,4-b]quinolin-4-amines as a new series of potent apoptosis inducers Original Research Article

216

Discovery and structure–activity relationship studies of a novel and specific peptide motif, pro-X-X-X-asp-X, as a platelet fibrinogen receptor antagonist Original Research Article

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Discovery and structure–activity relationship studies of indole derivatives as liver X receptor (LXR) agonists

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Discovery and structure–activity relationships of 2-benzylpyrrolidine-substituted aryloxypropanols as calcium-sensing receptor antagonists

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Discovery and structure–activity relationships of new steroidal compounds bearing a carboxy-terminal side chain as androgen receptor pure antagonists

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Discovery and structure–activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors

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Discovery and structure–activity relationships of novel sulfonamides as potent PTP1B inhibitors

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Discovery and structure-activity studies of a novel series of pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors

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Discovery and study of dinosaurs from Spain: The contribution of Albert F. de Lapparent

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Discovery and synthesis of a novel and selective drug-like P2X1 antagonist

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Discovery and synthesis of a novel series of quinoline-based thrombin receptor (PAR-1) antagonists

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Discovery and synthesis of a potent sulfonamide ETB selective antagonist

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Discovery and synthesis of novel phosphine-based ligands for aryl aminations

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Discovery and synthesis of tetrahydroindolone derived semicarbazones as selective Kv1.5 blockers

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Discovery and synthesis of tetrahydroindolone-derived carbamates as Kv1.5 blockers

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Discovery and the structural basis of a novel p21-activated kinase 4 inhibitor

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Discovery and Understanding of Transition-Metal-Catalyzed Aromatic Substitution Reactions

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Discovery and validation of new protein biomarkers for urothelial cancer: A prospective analysis: Theodorescu D, Wittke S, Ross MM, Walden M, Conaway M, Just I, Mischak H, Frierson HF, Department of Molecular Physiology, Mellon Prostate Cancer Institute,

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Discovery from combinatorial heterogeneous catalysis: A new class of catalyst for ethane oxidative dehydrogenation at low temperatures Original Research Article

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Discovery Learning Strategy in Geographical Education: A Sample of Lesson Design

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Discovery learning, representation, and explanation within a computer-based simulation: finding the right mix

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Discovery limits in prospective studies

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Discovery limits in prospective studies

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Discovery of (−)-6-[2-[4-(3-fluorophenyl)-4-hydroxy-1-piperidinyl]-1-hydroxyethyl]-3,4-dihydro-2(1H)-quinolinone—A potent NR2B-selective N-methyl d-aspartate (NMDA) antagonist for the treatment of pain

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Discovery of (2S)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-4-methyl-2-piperazinecarboxamide (MB243), a potent and selective melanocortin subtype-4 receptor agonist

240

Discovery of (naphthalen-4-yl)(phenyl)methanones and N-methyl-N-phenylnaphthalen-1-amines as new apoptosis inducers using a cell- and caspase-based HTS assay

241

Discovery of (R)-1-[2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol: A Novel NR1/2B Subtype Selective NMDA Receptor Antagonist

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Discovery of (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S,Z)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide (BMS-433796): A γ-secretase inhibitor with Aβ lowering activity in a transgenic mouse model of Alzheimer’s dis

243

Discovery of (Z)-2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives active against Haemonchus contortus and Ctenocephalides felis (cat flea)

244

Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor

245

Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays

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Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective αvβ3 inhibitor: Design, synthesis, and optimization Original Research Article

247

Discovery of 1-(4-phenoxypiperidin-1-yl)-2-arylaminoethanone stearoyl-CoA desaturase 1 inhibitors

248

Discovery of 1,1-dioxo-1,2,6-thiadiazine-5-carboxamide derivatives as cannabinoid-like molecules with agonist and antagonist activity Original Research Article

249

Discovery of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid diamides that increase CFTR mediated chloride transport

250

Discovery of 1,3-disubstituted-1H-pyrrole derivatives as potent Melanin-Concentrating Hormone Receptor 1 (MCH-R1) antagonists

251

Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors Original Research Article

252

Discovery of 1,7-cyclized indoles as a new class of potent and highly selective human β3-adrenergic receptor agonists with high cell permeability Original Research Article

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Discovery of 17,18O-rich material from meteorite by direct-imaging method using stigmatic-SIMS and 2D ion detector

254

Discovery of 1-amino-4-phenylcyclohexane-1-carboxylic acid and its influence on agonist selectivity between human melanocortin-4 and -1 receptors in linear pentapeptides

255

Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure–activity relationships of the 1- and 3-positions

256

Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors

257

Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV-1 agents

258

Discovery of 2,4,6-trisubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors

259

Discovery of 23 Natural Tubulysins from Angiococcus disciformis An d48 and Cystobacter SBCb004 Original Research Article

260

Discovery of 2-amino-6-carboxamidobenzothiazoles as potent Lck inhibitors

261

Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors

262

Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening

263

Discovery of 2-Phenyl-3-sulfonylphenyl-indole derivatives as a new class of selective COX-2 inhibitors Original Research Article

264

Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: Synthesis and SAR studies

265

Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-α production Original Research Article

266

Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13

267

Discovery of 3,5-bis(trifluoromethyl)benzyl l-arylglycinamide based potent CCR2 antagonists

268

Discovery of 3-acetyl-4-hydroxy-2-pyranone derivatives and their difluoridoborate complexes as a novel class of HIV-1 integrase Inhibitors Original Research Article

269

Discovery of 3-Amino-4-Chlorophenyl P1 as a novel and potent benzamidine mimic via solid-phase synthesis of an isoxazoline library

270

Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors

271

Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists

272

Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes

273

Discovery of 3-hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles as potent MEK1 inhibitors

274

Discovery of 3-OH-3-methylpipecolic hydroxamates: Potent orally active inhibitors of aggrecanase and MMP-13

275

Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1

276

Discovery of 4,5-Diphenyl-1,2,4-triazole Derivatives as a Novel Class of Selective Antagonists for the Human V1A Receptor Original Research Article

277

Discovery of 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2′-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors

278

Discovery of 4′-[(Imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/Angiotensin II receptor antagonists

279

Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR

280

Discovery of 4-aryl-2-oxo-2H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay

281

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure–activity relationships of the 7- and 5-, 6-, 8-positions

282

Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: Modifications of the 2- and 3-positions

283

Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11β-HSD1: Novel therapeutic agents for the treatment of metabolic syndrome

284

Discovery of 4-substituted-8-(2-hydroxy-2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a novel class of highly selective GlyT1 inhibitors with improved metabolic stability

285

Discovery of 5-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7-phenyl-(E)-2,3,6,7-tetrahydro-1,4-thiazepines as a new series of apoptosis inducers using a cell- and caspase-based HTS assay

286

Discovery of 5-HT6 receptor ligands based on virtual HTS

287

Discovery of 5-Hydroxyalkyl-4-phenylpyridines as a New Class of Glucagon Receptor Antagonists

288

Discovery of 60Ge and 64Se

289

Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors

290

Discovery of 7α-substituted dihydrotestosterones as androgen receptor pure antagonists and their structure–activity relationships Original Research Article

291

Discovery of a 7 second anomalous X-ray pulsar in the distant Milky Way

292

Discovery of a Binary Active Galactic Nucleus in the Ultraluminous Infrared Galaxy NGC 6240 Using Chandra

293

Discovery of a binary Centaur

294

Discovery of a c.370 Ma granitic gneiss clast from the Hwanggangri pebble-bearing phyllite in the Okcheon metamorphic belt, Korea

295

Discovery of a coherent 87.65-minute oscillation of the suspected cataclysmic variable NSV 2872 (Aur 2)

296

Discovery of a dihydropyrimidine series of molecules that selectively mimic the biological actions of calcitonin

297

Discovery of a dismembered metamorphic sole in the Saga ophiolitic mélange, South Tibet: Assessing an Early Cretaceous disruption of the Neo-Tethyan supra-subduction zone and consequences on basin closing

298

Discovery of a dopamine D4 selective PET ligand candidate taking advantage of a click chemistry based REM linker

299

Discovery of a double impact crater in Libya: the astrobleme of Arkenu

300

Discovery of a dust cloud next to (sigma)Orionis

301

Discovery of a faint R-band drop-out: A strongly reddened lensed star forming galaxy at z = 1.68

302

Discovery of a giant deep-sea valley in the Indian Ocean, off eastern Africa: The Tanzania channel

303

Discovery of a helium-core white dwarf progenitor

304

Discovery of a hidden BIF deposit in Anhui province, China by integrated geological and geophysical investigations

305

Discovery of a highly orally bioavailable c-5-[6-(4-Methanesulfonyloxyphenyl)hexyl]-2-methyl-1,3-dioxane-r-2-carboxylic acid as a potent hypoglycemic and hypolipidemic agent

306

Discovery of a highly potent series of oxazole-based phosphodiesterase 4 inhibitors

307

Discovery of a highly potent, functionally-selective muscarinic M1 agonist,WAY-132983 using rational drug design and receptor modelling

308

Discovery of a huge sector collapse at the Nisyros volcano, Greece, by on-land and offshore geological-structural data

309

Discovery of a Late Ordovician Foliomena fauna in the Tarim desert, Northwest China

310

Discovery of a Low-Mass Bipolar Molecular Outflow from L1014-IRS with the Submillimeter Array

311

Discovery of a luminous water megamaser in the FR II radiogalaxy 3C 403

312

Discovery of a magnetic field in the Slowly Pulsating B star Cassiopeiae

313

Discovery of a Magnetic Ionic Liquid [bmim]FeCl4

314

Discovery of a mass grave of Napoleonic period in Lithuania (1812, Vilnius)

315

Discovery of a Mesolithic burial near the painted rock-shelter of Ban Tha Si (Lampang province, Northern Thailand): Implications for regional mortuary practices

316

Discovery of a missing disease spreader

317

Discovery of a muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors among 2-[(1S,3S)-3-sulfonylaminocyclopentyl]phenylacetamide derivatives Original Research Article

318

Discovery of a N′-hydroxyphenylformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor

319

Discovery of a Nearby Halo White Dwarf with Proper Motion (mu) = 2n55 yr^-1

320

Discovery of a Neoproterozoic basin in the Prydz belt in East Antarctica and its implications for Gondwana assembly and ultrahigh temperature metamorphism

321

Discovery of a new 2.3 s isomer in neutron-rich 174Tm

322

Discovery of a new catalytically active and selective zeolite (ITQ-30) by high-throughput synthesis techniques

323

Discovery of a new chemical lead for a matrix metalloproteinase inhibitor Original Research Article

324

Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies

325

Discovery of a new class of p38 kinase inhibitors

326

Discovery of a new class of potent, selective, and orally active prostaglandin D2 receptor antagonists Original Research Article

327

Discovery of A New Class of Pulsating Stars: Gravity-Mode Pulsators among Subdwarf B Stars

328

Discovery of a new cyclooxygenase-2 lead compound through 3-D database searching and combinatorial chemistry

329

Discovery of a new element ‘nipponium’: re-evaluation of pioneering works of Masataka Ogawa and his son Eijiro Ogawa

330

Discovery of a new Fe-type nitrile hydratase efficiently hydrating aliphatic and aromatic nitriles by genome mining

331

Discovery of a new hydrothermal vent based on an underwater, high-resolution geophysical survey

332

Discovery of a new insecticide lead by optimizing a target-diverse scaffold: Tetrazolinone derivatives Original Research Article

333

Discovery of a New Role of Human Resistin in Hepatocyte Low-Density Lipoprotein Receptor Suppression Mediated in Part by Proprotein Convertase Subtilisin/Kexin Type 9

334

Discovery of a new species of Lonchodryinus from Madagascar (Hymenoptera, Dryinidae)

335

Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1)

336

Discovery of a novel abl tyrosine kinase inhibitor that selectively induces apoptosis of bcr-abl-positive leukemic cells

337

Discovery of a novel and potent series of dianilinopyrimidineurea and urea isostere inhibitors of VEGFR2 tyrosine kinase

338

Discovery of a novel and potent series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases

339

Discovery of a novel antimicrobial peptide using membrane binding-based approach

340

Discovery of a novel benzyloxyisoquinoline derivative with potent anti-Helicobacter pylori activity

341

Discovery of a novel bicycloproline P2 bearing peptidyl α-ketoamide LY514962 as HCV protease inhibitor

342

Discovery of a novel CCR3 selective antagonist

343

Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor α (PPARα) agonists

344

Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitors

345

Discovery of a novel class of benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain

346

DISCOVERY OF A NOVEL CLASS OF BK CHANNEL OPENERS: ENANTIOSPECIFIC SYNTHESIS AND BK CHANNEL OPENING ACTIVITY OF 3-(5-CHLORO-2-HYDROXYPHENYL)-1,3-DIHYDRO-3-HYDROXY-6-(TRIFLUOROMETHYL)-2H-INDOL-2-ONE

347

Discovery of a novel class of PPARδ partial agonists

348

Discovery of a novel class of selective human CB1 inverse agonists

349

Discovery of a Novel Family of CDK Inhibitors with the Program LIDAEUS: Structural Basis for Ligand-Induced Disordering of the

350

Discovery of a novel indole series of EP1 receptor antagonists by scaffold hopping

351

Discovery of a novel lead structure for anti-malarials Original Research Article

352

Discovery of a novel one-step RuO4-catalysed tandem oxidative polycyclization/double spiroketalization process. Access to a new type of polyether bis-spiroketal compound displaying antitumour activity

353

Discovery of a novel potent Na+/Ca2+ exchanger inhibitor: design, synthesis and structure–activity relationships of 3,4-dihydro-2(1H)-quinazolinone derivatives

354

Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TRβ subtype-selective thyromimetics

355

Discovery of a novel series of DHODH inhibitors by a docking procedure and QSAR refinement

356

Discovery of a novel series of inhibitors of human cytomegalovirus primase

357

Discovery of a novel series of nonsteroidal androgen receptor modulators: 5- or 6-oxachrysen-2-ones

358

Discovery of a novel series of Notch-sparing γ-secretase inhibitors

359

Discovery of a novel series of selective MMP inhibitors: Identification of the γ-sulfone-thiols

360

Discovery of a novel small molecule binding site of human survivin

361

Discovery of a novel small molecule, 1-ethoxy-3-(3,4-methylenedioxyphenyl)-2-propanol, that induces apoptosis in A549 human lung cancer cells Original Research Article

362

Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase

363

Discovery of a novel tetrahydroacridine acetylcholinesterase inhibitor through an indexed combinatorial library Original Research Article

364

Discovery of a novel, potent and orally active series of γ-lactams as selective NK1 antagonists

365

Discovery of a novel, potent and selective human β3-adrenergic receptor agonist

366

Discovery of a nuclease-resistant, non-natural dinucleotide that inhibits HIV-1 integrase

367

Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry

368

Discovery of a potent and selective agonist of the prostaglandin EP4 receptor

369

Discovery of a potent and selective Aurora kinase inhibitor

370

Discovery of a potent and selective c-Kit inhibitor for the treatment of inflammatory diseases

371

Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile

372

Discovery of a potent and selective series of pyrazole bacterial methionyl-tRNA synthetase inhibitors

373

Discovery of a potent and selective αvβ3 integrin antagonist with strong inhibitory activity against neointima formation in rat balloon injury model

374

Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping

375

Discovery of a potent phenolic N1-benzylidene–pyridinecarboxamidrazone selective against Gram-positive bacteria

376

Discovery of a potent, non-triketone type inhibitor of 4-hydroxyphenylpyruvate dioxygenase

377

Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine

378

Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI)

379

Discovery of a prehistoric site at Sao Din (Nanoi, Nan province, Northern Thailand): Stone tools and new geological insights

380

Discovery of a Proneurogenic, Neuroprotective Chemical

381

Discovery of a recent, natural whale fall on the continental slope off Anvers Island, western Antarctic Peninsula

382

Discovery of a recurrent lava lake on Saunders Island (South Sandwich Islands) using AVHRR imagery

383

Discovery of a reductase-producing strain recombinant E. coli CCZU-A13 using colorimetric screening and its whole cell-catalyzed biosynthesis of ethyl (R)-4-chloro-3-hydroxybutanoate

384

Discovery of a Secreted Tumor Suppressor Provides a Promising Therapeutic Strategy for Follicular Lymphoma

385

Discovery of a series of (4,5-Dihydroimidazol-2-yl)-biphenylamine 5-HT7 agonists

386

Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists Original Research Article

387

Discovery of a series of aminopiperidines as novel iNOS inhibitors

388

Discovery of a series of pyrrolidine-based endothelin receptor antagonists with enhanced ETA receptor selectivity Original Research Article

389

Discovery of a Small Molecule that Inhibits the Interaction of Anthrax Edema Factor with Its Cellular Activator, Calmodulin Original Research Article

390

Discovery of a strong magnetic field in the rapidly rotating B2Vn star HR7355

391

Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: Structure–activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor

392

Discovery of a Substrate Selectivity Switch in Tyrosine Ammonia-Lyase, a Member of the Aromatic Amino Acid Lyase Family Original Research Article

393

Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor

394

Discovery of a Thermophilic Protein Complex Stabilized by Topologically Interlinked Chains

395

Discovery of a Tight Brown Dwarf Companion to the Low-Mass Star LHS 2397a

396

Discovery of a Two-Component Monooxygenase SnoaW/SnoaL2 Involved in Nogalamycin Biosynthesis Original Research Article

397

Discovery of a very extended X-ray halo around a quiescent spiral galaxy – The “missing link” of galaxy formation

398

Discovery of a Wide, Low-Mass Binary System in Upper Scorpius

399

Discovery of a young asteroid cluster associated with P/2012 F5 (Gibbs)

400

Discovery of a z = 6.17 galaxy from CFHT and VLT observations

401

Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection

402

Discovery of actinium, thorium, protactinium, and uranium isotopes

403

Discovery of active hydrothermal venting in Lake Taupo, New Zealand

404

Discovery of active site of vinblastine as application of nanotechnology in medicine

405

Discovery of active site of vinblastine as application of nanotechnology in medicine

406

Discovery of adamantane ethers as inhibitors of 11β-HSD-1: Synthesis and biological evaluation

407

Discovery of ADC absorption in the LMXB XB 1323-619 with XMM-Newton Original Research Article

408

Discovery of additional lead-rich stars

409

Discovery of agglutinated benthic foraminifera in Devonian black shales and their relevance for the redox state of ancient seas

410

Discovery of AICAR Tfase inhibitors that disrupt requisite enzyme dimerization

411

Discovery of alcohol dehydrogenase from mushrooms and application to alcoholic beverages

412

Discovery of amide and heteroaryl isosteres as carbamate replacements in a series of orally active γ-secretase inhibitors

413

Discovery of amido-benzisoxazoles as potent c-Kit inhibitors

414

Discovery of amino acid amides as new substrates for α-amino-ɛ-caprolactam racemase from Achromobacter obae

415

Discovery of amino-acetonitrile derivatives, a new class of synthetic anthelmintic compounds

416

Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling Original Research Article

417

Discovery of an adakite-like pluton near Dongqiyishan (Beishan, NW China) — Its age and tectonic significance

418

Discovery of an alkaline orthogneiss in the eclogite-bearing Cellier Unit (Champtoceaux Complex, Armorican Massif): a new witness of the Ordovician rifting

419

DISCOVERY OF AN ALTERNATIVELY SPLICED FORM OF BRAIN NATRIURETIC PEPTIDE: CHARACTERIZATION AND FUNCTION

420

Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones

421

Discovery of an archaic Homo sapiens skullcap in Northeast Mongolia

422

Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry

423

Discovery of an Autunian macroflora and lithostratigraphic re-investigation on the western border of the Lodève Permian basin (Mont Sénégra, Hérault, France). Paleoenvironmental implications

424

Discovery of an endophytic alga in Ginkgo biloba

425

Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity

426

Discovery of an ice cave in the Yatude Valley, Langhovde, Dronning Maud Land, East Antarctica

427

Discovery of an imidazopyridine-containing 1,4-benzodiazepine nonpeptide vitronectin receptor (αvβ3) antagonist with efficacy in a restenosis model

428

Discovery of an in situ carbocationic system using trityl chloride as a homogeneous organocatalyst for the solvent-free condensation of β-naphthol with aldehydes and amides/thioamides/alkyl carbamates in neutral media

429

Discovery of an Iron-Regulated Citrate Synthase in Staphylococcus aureus Original Research Article

430

Discovery of an M4 Spectroscopic Binary in Upper Scorpius: A Calibration Point for Young Low-Mass Evolutionary Models

431

Discovery of an N-(2-aminopyridin-4-ylmethyl)nicotinamide derivative: a potent and orally bioavailable NCX inhibitor Original Research Article

432

Discovery of an Optically Faint Quasar at z = 5.70 and Implications for the Faint Endof the Quasar Luminosity Function

433

Discovery of an orally bioavailable alkyl oxadiazole β3 adrenergic receptor agonist

434

Discovery of an orally efficaceous 4-phenoxypyrrolidine-based BACE-1 inhibitor

435

Discovery of an outcropping Mass Transport Deposit (MTD) in the Palaeogene subalpine synclines of southeastern France: Implications on flexural sub-basin deformation

436

Discovery of an Ultracool Subdwarf: LSR 1425+7102, the First Star with Spectral Type sdM8.0

437

Discovery of an Upper Miocene Vertebrate fauna near Tizi N’Tadderht, Skoura, Ouarzazate Basin (Central High Atlas, Morocco)

438

Discovery of Antagonist Peptides against Bacterial Helicase-Primase Interaction in B. stearothermophilus by Reverse Yeast Three-Hybrid Original Research Article

439

Discovery of Antagonists of PqsR, a Key Player in 2-Alkyl-4-quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa Original Research Article

440

Discovery of anticonvulsant activity of abietic acid through application of linear discriminant analysis

441

Discovery of anti-influenza A virus activity of a corynanthe-type indole alkaloid, hirsutine, in vitro and the structure-activity relationship of natural and synthetic analogs

442

Discovery of antirhinoviral leads by screening a combinatorial library of ureas prepared using covalent scavengers

443

Discovery of Archaean crust within the Akitkan orogenic belt of the Siberian craton: New insight into its architecture and history

444

Discovery of azetidinone acids as conformationally-constrained dual PPARα/γ agonists

445

Discovery of Baeyer–Villiger monooxygenases from photosynthetic eukaryotes

446

Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90

447

Discovery of benzo[g]indol-3-carboxylates as potent inhibitors of microsomal prostaglandin E2 synthase-1 Original Research Article

448

Discovery of benzoylpiperazines as a novel class of potent and selective GlyT1 inhibitors

449

Discovery of betamethasone 17α-carbamates as dissociated glucocorticoid receptor modulators in the rat Original Research Article

450

Discovery of Bioactive Small-Molecule Inhibitor of Poly ADP-Ribose Polymerase: Implications for Energy-Deficient Cells Original Research Article

451

Discovery of bitriazolyl compounds as novel antiviral candidates for combating the tobacco mosaic virus

452

Discovery of brain penetrant, soluble, pyrazole amide EP1 receptor antagonists

453

Discovery of cancer biomarkers through the use of mouse models

454

Discovery of candidate phospholipid biomarkers in human lipoproteins with coronary artery disease by flow field-flow fractionation and nanoflow liquid chromatography–tandem mass spectrometry

455

Discovery of carboxypeptidase Y as a catalyst for the incorporation of sterically demanding α-fluoroalkyl amino acids into peptides

456

Discovery of cesium, lanthanum, praseodymium and promethium isotopes

457

Discovery of CH4-rich high-pressure fluid inclusions hosted in analcime from Dongying depression, China

458

Discovery of chromium, manganese, nickel, and copper isotopes

459

Discovery of classes among deep level centers in gallium arsenide

460

Discovery of co2 ice and leading–trailing spectral asymmetry on the uranian satellite ariel

461

Discovery of conformationally rigid 3-azabicyclo[3.1.0]hexane-derived dipeptidyl peptidase-IV inhibitors

462

Discovery of Conserved and Novel MicroRNAs in Galdieria sulphuraria

463

Discovery of Conserved Sequence Patterns Using a Stochastic Dictionary Model

464

Discovery of coumarin as the predominant allelochemical in Gliricidia sepium

465

Discovery of CP-199,330 and CP-199,331: Two potent and orally efficacious cysteinyl LT1 receptor antagonists devoid of liver toxicity

466

Discovery of cubic diamond and sp2 carbon micro-particles in “Chelyabinsk” meteorite by Raman micro-mapping

467

Discovery of cyclopentane- and cyclohexane-trans-1,3-diamines as potent melanin-concentrating hormone receptor 1 antagonists

468

Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists

469

Discovery of diaminobutane derivatives as Ca2+-permeable AMPA receptor antagonists Original Research Article

470

Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists

471

Discovery of diphenylcarbamate derivatives as highly potent and selective IP receptor agonists: Orally active prostacyclin mimetics. Part 3

472

Discovery of dipolar-glassy state in a newly found solid–solution system of C5NH6(BF4)1−x(PF6)x

473

Discovery of direct inhibitor of KRAS oncogenic protein by natural products: a combination of pharmacophore search, molecular docking, and molecular dynamic studies

474

Discovery of distyly in Narcissus (Amaryllidaceae)

475

Discovery of dividing neurons in human brains excites researchers

476

Discovery of doubly-magic 48Ni at GANIL Original Research Article

477

Discovery of Drug-Resistant and Drug-Sensitizing Mutations in the Oncogenic PI3K Isoform p110α

478

Discovery of Dual Inhibitors of the Immune Cell PI3Ks p110δ and p110γ: a Prototype for New Anti-inflammatory Drugs Original Research Article

479

Discovery of dysprosium, holmium, erbium, thulium, and ytterbium isotopes

480

Discovery of Early Optical Emission from GRB 021211

481

Discovery of Early Paleozoic eclogite from the East Kunlun, Western China and its tectonic significance

482

Discovery of effective solvents for platelet-type graphite nanofibers Original Research Article

483

Discovery of Erysiphe platani anamorph on Platanus × hispanica from Brazil

484

Discovery of factors influencing citation impact based on a soft fuzzy rough set model

485

Discovery of factors influencing patent value based on machine learning in patents in the field of nanotechnology

486

Discovery of feature-based hot spots using supervised clustering

487

Discovery of FK453, a novel non-xanthine adenosine A1 receptor antagonist

488

Discovery of FR115092 : A novel antinephritic agent

489

Discovery of FR166124, a novel water-soluble pyrazolo-[1,5-α]pyridine adenosine A1 receptor antagonist

490

Discovery of functional protein groups by clustering community links and integration of ontological knowledge

491

Discovery of fuzzy quantitative sequential patterns with multiple minimum supports and adjustable membership functions

492

Discovery of galectin ligands in fully randomized combinatorial one-bead-one-compound (glyco)peptide libraries

493

Discovery of gallium, germanium, lutetium, and hafnium isotopes

494

Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148 Original Research Article

495

Discovery of Habritys brevicornis (Ratzeburg, 1844) (Hymenoptera: Pteromalidae) in the Middle-East

496

Discovery of halogenated eurypamide B analogues as inhibitors of lipid droplet accumulation in macrophages

497

Discovery of hazardous foreign bodies observed during anesthetic practice

498

Discovery of Helicobacter pylori shikimate kinase inhibitors: Bioassay and molecular modeling Original Research Article

499

Discovery of heteroaryl sulfonamides as new EP1 receptor selective antagonists Original Research Article

500

Discovery of heterobicyclic templates for novel metabotropic glutamate receptor subtype 5 antagonists

501

Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach

502

Discovery of hexacoordinate hypervalent carbon compounds: Density functional study

503

Discovery of Hg–Cu-bearing metal-sulfide assemblages in a primitive H-3 chondrite: Towards a new insight in early solar system processes

504

Discovery of hidden correlations in a local transaction database based on differences of correlations

505

Discovery of high utility itemsets from on-shelf time periods of products

506

Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists

507

Discovery of highly potent Src SH2 binders: Structure–activity studies and X-ray structures

508

Discovery of highly potent, selective, orally bioavailable, metabotropic glutamate subtype 5 (mGlu5) receptor antagonists devoid of cytochrome P450 1A2 inhibitory activity

509

Discovery of highly selective EP4 receptor agonists that stimulate new bone formation and restore bone mass in ovariectomized rats

510

Discovery of high-pressure granulite-facies metamorphism in northern Vietnam: Constraints on the Permo-Triassic Indochinese continental collision tectonics

511

Discovery of historical Tainan: a digital approach

512

Discovery of Holocene millennial climate cycles in the Asian continental interior: Has the sun been governing the continental climate?

513

Discovery of human CCR5 antagonists containing hydantoins for the treatment of HIV-1 infection

514

Discovery of human zinc deficiency: 50 years later

515

Discovery of human zinc deficiency: impact on human health

516

Discovery of hydrometeorological patterns

517

Discovery of hydrothermal sulfide mineralization from southern Kermadec arc volcanoes (SW Pacific)

518

Discovery of hydroxamic acid analogs as dual inhibitors of phosphodiesterase-1 and -5

519

Discovery of imidazo[1,2-c]pyrimidin-5(6H)-one heterosubstituted nucleoside analogues with potent activity against human hepatitis B virus in

520

Discovery of imidazole carboxamides as potent and selective CCK1R agonists

521

Discovery of imidazole glycerol phosphate dehydratase inhibitors through 3-D database searching

522

Discovery of imidazole vinyl pyrimidines as a novel class of kinase inhibitors which inhibit Tie-2 and are orally bioavailable

523

Discovery of imidazolidine-2,4-dione-linked HIV protease inhibitors with activity against lopinavir-resistant mutant HIV Original Research Article

524

Discovery of Iminobenzimidazole Derivatives as Novel Cytotoxic Agents

525

Discovery of immune molecules and their crucial functions in shrimp immunity

526

Discovery of Improved EGF Agonists Using a Novel In Vitro Screening Platform

527

Discovery of impurities existing state in carbide slag by chemical dissociation

528

Discovery of indenopyrazoles as EGFR and VEGFR-2 tyrosine kinase inhibitors by in silico high-throughput screening

529

Discovery of Independence: South Asia at 63

530

Discovery of indole-containing tetracycles as a new scaffold for androgen receptor ligands

531

Discovery of inhibitors of brassinin oxidase based on the scaffolds of the phytoalexins brassilexin and wasalexin Original Research Article

532

Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target

533

Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design

534

Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis

535

Discovery of Inhibitors that Elucidate the Role of UCH-L1 Activity in the H1299 Lung Cancer Cell Line Original Research Article

536

Discovery of insect parasitism and subsequent development of parasitoid research in Japan

537

Discovery of invisible extra fronts in single-component frontal analysis in liquid chromatography

538

Discovery of iridium and other element anomalies near the 1908 Tunguska explosion site

539

Discovery of IRL 3461: a novel and potent endothelin antagonist with balanced ETA/ETB affinity

540

Discovery of iron-K absorption lines from the transient jets GRS 1915+105 and GRO J1655-40 Original Research Article

541

Discovery of isotopes of elements with

542

Discovery of isotopes of the transuranium elements with 93≤Z≤98

543

Discovery of isotopes with

544

Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials

545

Discovery of Jadeite-Jade in Guatemala Confirmed by Non-Destructive Raman Microscopy

546

Discovery of jarosite within the Mawrth Vallis region of Mars: Implications for the geologic history of the region

547

Discovery of jet quenching and beyond Original Research Article

548

Discovery of jet quenching at RHIC and the opacity of the produced gluon plasma Original Research Article

549

Discovery of Kibdelomycin, A Potent New Class of Bacterial Type II Topoisomerase Inhibitor by Chemical-Genetic Profiling in Staphylococcus aureus Original Research Article

550

Discovery of Kilohertz Quasi-periodic Oscillations and Shifted Frequency Correlations in the Accreting Millisecond Pulsar XTE J1807294

551

Discovery of L-740,515, a potent thienopyridine cysLT1 receptor (LTD4 receptor) antagonist

552

Discovery of L-755,507: A subnanomolar human β3 adrenergic receptor agonist

553

Discovery of L-791,943: A potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor

554

Discovery of Latest Devonian/Earliest Mississippian microfossils in San Salvador Patlanoaya (Puebla, Mexico); biogeographic and geodynamic consequences

555

Discovery of LB30057, a benzamidrazone-based selective oral thrombin inhibitor

556

Discovery of long-acting N-(cyanomethyl)-N-alkyl-l-prolinamide inhibitors of dipeptidyl peptidase IV Original Research Article

557

Discovery of low mucus adhesion surfaces

558

Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)

559

Discovery of magnetic field variations with the 12.1-minute pulsation period of the roAp star (gamma) Equulei

560

Discovery of male of Proconura persica Delvare (Hymenoptera: Chalcididae), recently described from Iran

561

Discovery of mass spectral characteristics and automatic identification of wax esters from gas chromatography mass spectrometry data

562

Discovery of maximum length frequent itemsets

563

Discovery of melanin-concentrating hormone receptor R1 antagonists using high-throughput synthesis Original Research Article

564

Discovery of Messinian canyons and new seismic stratigraphic model, offshore Provence (SE France): Implications for the hydrographic network reconstruction

565

Discovery of metastable tetragonal disordered phase upon phase transitions in the equiatomic nanostructured FePd alloy Original Research Article

566

Discovery of micromolar PDE IV inhibitors that exhibit much reduced affinity for the [3H]rolipram binding site: 3-norbornyloxy-4-methoxyphenylmethylene oxindoles

567

Discovery of microscopic evidence for shock metamorphism at the Serpent Mound structure, south-central Ohio: confirmation of an origin by impact

568

Discovery of Middle Jurassic (Bajocian) Radiolaria from the sedimentary cover of the Vedi ophiolite (Lesser Caucasus, Armenia)

569

Discovery of Miocene adakitic dacite from the Eastern Pontides Belt (NE Turkey) and a revised geodynamic model for the late Cenozoic evolution of the Eastern Mediterranean region

570

Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme induction

571

Discovery of N-(2-aryl-cyclohexyl) substituted spiropiperidines as a novel class of GlyT1 inhibitors

572

Discovery of N-(2-hydroxy-2-aryl-cyclohexyl) substituted spiropiperidines as GlyT1 antagonists with improved pharmacological profile

573

Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the α7 nicotinic acetylcholine receptor: In vitro and in vivo activity

574

Discovery of narrow X-ray absorption features from the low-mass X-ray binary X 1254-690 with XMM-Newton

575

Discovery of neurosteroid glucuronides in mouse brain Original Research Article

576

Discovery of new angiotensin converting enzyme (ACE) inhibitors from medicinal plants to treat hypertension using an in vitro assay

577

Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design

578

Discovery of New Bioactive Secondary Metabolites from Psychrophilic Microorganisms — Mini Review

579

Discovery of new C3aR ligands. Part 1: Arginine derivatives

580

Discovery of new C3aR ligands. Part 2: Amino-piperidine derivatives

581

Discovery of new catalytic materials for the water–gas shift reaction by high-throughput experimentation Original Research Article

582

Discovery of new chemical leads for prostaglandin D2 receptor antagonists

583

Discovery of new chemical leads for selective EP1 receptor antagonists Original Research Article

584

Discovery of new diphenyloxazole derivatives containing a pyrrolidine ring: Orally active prostacyclin mimetics. Part 2

585

Discovery of New Drugs Against Tuberculosis: History Guides

586

Discovery of new fuel-lean NO reduction catalyst leads using combinatorial methodologies

587

Discovery of new Gram-negative antivirulence drugs: Structure and properties of novel E. coli WaaC inhibitors

588

Discovery of new hydrothermal vent sites in Bransfield Strait, Antarctica

589

Discovery of new hydrothermal vent sites in Bransfield Strait, Antarctica

590

Discovery of new inhibitors of aldose reductase from molecular docking and database screening Original Research Article

591

Discovery of new Milky Way star cluster candidates in the 2MASS Point Source Catalog. II. Physical properties of the star cluster CC 01

592

Discovery of new MurF inhibitors via pharmacophore modeling and QSAR analysis followed by in-silico screening Original Research Article

593

Discovery of new paraffin isomerization catalysts based on SO42−/ZrO2 and WOx/ZrO2 applying combinatorial techniques

594

Discovery of new peptide-Based catalysts for the direct asymmetric aldol reaction

595

Discovery of new phase and analysis of phase relationships in BaBiO3 with thermal analyses

596

Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53 Original Research Article

597

Discovery of new small molecules that influence neuroblast cell migration from the subventricular zone

598

Discovery of N-Hydroxy-2-(2-oxo-3-pyrrolidinyl)acetamides as potent and selective inhibitors of tumor necrosis factor-α converting enzyme (TACE)

599

Discovery of non-A, non-B hepatitis and identification of its etiology

600

Discovery of non-carbohydrate inhibitors of aminoglycoside-modifying enzymes Original Research Article

601

Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site

602

Discovery of non-peptidic P2–P3 butanediamide renin inhibitors with high oral efficacy Original Research Article

603

Discovery of nonsteroidal glucocorticoid receptor ligands based on 6-indole-1,2,3,4-tetrahydroquinolines

604

Discovery of non-steroidal mifepristone mimetics: Pyrazoline-based PR antagonists

605

Discovery of non-Zwitterionic GABAA receptor full agonists and a superagonist

606

Discovery of novel 1,2,3,4-tetrahydroisoquinolines and 3,4-dihydroisoquinoline-1(2H)-ones as potent and selective inhibitors of KDR: Synthesis, SAR, and pharmacokinetic properties

607

Discovery of Novel 1,2,3-Triazole Analogues as Anti-Tuberculosis agents Using 3D QSAR, Molecular Docking, and In Silico ADMET Screening

608

Discovery of novel 1-arylmethyl pyrrolidin-2-yl ethanol amines as calcium-sensing receptor antagonists

609

Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56Lck inhibitors

610

Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties

611

Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases

612

Discovery of novel 8-azoniabicyclo[3.2.1]octane carbamates as muscarinic acetylcholine receptor antagonists

613

Discovery of novel and orally active NR2B-selective N-methyl-d-aspartate (NMDA) antagonists, pyridinol derivatives with reduced HERG binding affinity

614

Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors

615

Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1

616

Discovery of novel and selective tertiary alcohol containing inhibitors of the norepinephrine transporter

617

Discovery of novel aspartyl ketone dipeptides as potent and selective caspase-3 inhibitors

618

Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains

619

Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease Original Research Article

620

Discovery of novel biaryl heterocyclic EP1 receptor antagonists

621

Discovery of novel conformationally constrained tropane-based biaryl and arylacetylene ligands as potent and selective norepinephrine transporter inhibitors and potential antidepressants

622

Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1β synthesis

623

Discovery of novel dialkyl substituted thiophene inhibitors of HCV by in silico screening of the NS5B RdRp

624

Discovery of novel dual functional agent as PPARγ agonist and 11β-HSD1 inhibitor for the treatment of diabetes Original Research Article

625

Discovery of novel FMS kinase inhibitors as anti-inflammatory agents

626

Discovery of Novel Glucagon Receptor Antagonists Using Combined Pharmacophore Modeling and Docking

627

Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-α-induced VCAM-1 expression

628

Discovery of novel heterocyclic factor VIIa inhibitors

629

Discovery of novel homogeneous rare earth catalysts by IR-thermography: epoxide opening with alcohols and Baeyer–Villiger oxidations with hydrogen peroxide Original Research Article

630

Discovery of novel hydantoins as selective non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)

631

Discovery of novel hydroxamates as highly potent tumor necrosis factor-α converting enzyme inhibitors. Part II: Optimization of the S3′ pocket

632

Discovery of novel hydroxy pyrazole based factor IXa inhibitor

633

Discovery of novel hydroxy-thiazoles as HIF-α prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation

634

Discovery of novel indazole-linked triazoles as antifungal agents

635

Discovery of novel inhibitors of 11β-hydroxysteroid dehydrogenase type 1 by docking and pharmacophore modeling

636

Discovery of novel inhibitors of ghrelin O-acyltransferase enzyme: an in-silico approach

637

Discovery of novel isatin-based thiosemicarbazones: synthesis, antibacterial, antifungal, and antimycobacterial screening

638

Discovery of novel isothiazole inhibitors of the TrkA kinase: Structure–activity relationship, computer modeling, optimization, and identification of highly potent antagonists

639

Discovery of novel isoxazolines as anti-tuberculosis agents

640

Discovery of novel low molecular weight inhibitors of IMPDH via virtual needle screening

641

Discovery of Novel Mastitis-Related SNP and RNA Splicing on HSF1 Gene in Chinese Holstein Cattle

642

Discovery of novel modulators of metabotropic glutamate receptor subtype-5 Original Research Article

643

Discovery of novel neuronal voltage-Dependent calcium channel blockers based on emopamil left hand as a bioactive template

644

Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors

645

Discovery of novel nonpeptide tricyclic inhibitors of ras farnesyl protein transferase Original Research Article

646

Discovery of novel non-peptidic ketopiperazine-based renin inhibitors Original Research Article

647

Discovery of novel nonsteroidal glucocorticoid receptor modulators

648

Discovery of novel orally active ureido NPY Y5 receptor antagonists

649

Discovery of Novel Peptidomimetics for Brain-Derived Neurotrophic Factor using Phage Display Technology

650

Discovery of Novel Phosphonic Acid Derivatives as New Chemical Leads for Inhibitors of TNF-α production Original Research Article

651

Discovery of novel phosphorus-containing steroids as selective glucocorticoid receptor antagonist

652

Discovery of novel potent and selective dipeptide hepatitis C virus NS3/4A serine protease inhibitors

653

Discovery of novel PRL-3 inhibitors based on the structure-based virtual screening

654

Discovery of novel prostaglandin analogs of PGE2 as potent and selective EP2 and EP4 receptor agonists

655

Discovery of novel PTP1b inhibitors

656

Discovery of novel purine derivatives with potent and selective inhibitory activity against c-Src tyrosine kinase Original Research Article

657

Discovery of novel series of benzoic acid derivatives containing biphenyl ether moiety as potent and selective human β3-adrenergic receptor agonists: Part IV

658

Discovery of novel sesquiterpenoids from a gorgonian Menella sp.

659

Discovery of novel tetrahydroisoquinoline derivatives as potent and selective factor Xa inhibitors

660

Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation and structure–activity relationships. Part 2 Original Research Article

661

Discovery of novel thiourea derivatives as potent and selective β3-adrenergic receptor agonists Original Research Article

662

Discovery of novel trans-3,5-disubstituted pyrrolidinylthio-1β-methylcarbapenems Original Research Article

663

Discovery of Novel Transcriptional and Epigenetic Targets in APL by Global ChIP Analyses: Emerging Opportunity and Challenge

664

Discovery of novel α-glucosidase inhibitors based on the virtual screening with the homology-modeled protein structure Original Research Article

665

Discovery of novel, non-acidic 1,5-biaryl pyrrole EP1 receptor antagonists

666

Discovery of novel, orally active dual NK1/NK2 antagonists

667

Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors

668

Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonists

669

Discovery of N-phenyl nicotinamides as potent inhibitors of Kdr

670

Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists

671

Discovery of Nuclear DNA-like RNA (dRNA, hnRNA) and Ribonucleoproteins Particles Containing hnRNA

672

Discovery of Opisthorchis viverrini metacercariae in freshwater fish in southern Cambodia

673

Discovery of orally active butyrolactam 11β-HSD1 inhibitors

674

Discovery of orally active prostaglandin D2 receptor antagonists

675

Discovery of orally active pyrrolopyridine- and aminopyridine-based Met kinase inhibitors

676

Discovery of orally available spirodiketopiperazine-based CCR5 antagonists Original Research Article

677

Discovery of orally bioavailable and novel urea agonists of the high affinity niacin receptor GPR109A

678

Discovery of orally bioavailable NK1 receptor antagonists

679

Discovery of osteoblast-associated genes using cDNA microarrays

680

Discovery of OT4003, a novel, potent, and orally active cys-LT1 receptor antagonist Original Research Article

681

Discovery of Oxysterol-Derived Pharmacological Chaperones for NPC1: Implication for the Existence of Second Sterol-Binding Site Original Research Article

682

Discovery of palladium, antimony, tellurium, iodine, and xenon isotopes

683

Discovery of para-alkylthiophenoxyacetic acids as a novel series of potent and selective PPARδ agonists

684

Discovery of Peptoid Ligands for Anti-Aquaporin 4 Antibodies Original Research Article

685

Discovery of Permian sporopollen from Daftar, Taxkorgan, Xinjiang and their geological implications

686

Discovery of phenyl alanine derived ketoamides carrying benzoyl residues as novel calpain inhibitors

687

Discovery of Picomolar Slow Tight-Binding Inhibitors of α-Fucosidase

688

Discovery of Picomolar Slow Tight-Binding Inhibitors of α-Fucosidase Original Research Article

689

Discovery of pinoresinol reductase genes in sphingomonads

690

Discovery of piperazinylimidazo[1,2-a]pyridines as novel S4 binding elements for orally active Factor Xa inhibitors Original Research Article

691

Discovery of piperidine carboxamide TRPV1 antagonists

692

Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors

693

Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries Original Research Article

694

Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries Original Research Article

695

Discovery of potent and cell-active allosteric dual Akt 1 and 2 inhibitors

696

Discovery of potent and orally active MTP inhibitors as potential anti-obesity agents

697

Discovery of potent and orally active tricyclic-based FBPase inhibitors Original Research Article

698

Discovery of potent and orally bioavailable heterocycle-based β3-adrenergic receptor agonists, potential therapeutics for the treatment of obesity

699

Discovery of potent and orally bioavailable N,N′-diarylurea antagonists for the CXCR2 chemokine receptor

700

Discovery of Potent and Reversible Monoacylglycerol Lipase Inhibitors Original Research Article

701

Discovery of Potent and Selective Covalent Inhibitors of JNK Original Research Article

702

Discovery of potent and selective inhibitors of 11β-HSD1 for the treatment of metabolic syndrome

703

Discovery of potent and selective orally bioavailable β-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors

704

Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling Original Research Article

705

Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors

706

Discovery of potent and selective phenylalanine derived CCR3 antagonists. Part 1

707

Discovery of potent and selective phenylalanine derived CCR3 receptor antagonists. Part 2

708

Discovery of potent and selective PKC-θ inhibitors

709

Discovery of potent and selective small molecule NPY Y5 receptor antagonists

710

Discovery of potent and selective succinyl hydroxamate inhibitors of matrix metalloprotease-3 (Stromelysin-1)

711

Discovery of potent and selective β-homophenylalanine based dipeptidyl peptidase IV inhibitors

712

Discovery of potent and stable conformationally constrained analogues of the MCH R1 antagonist SB-568849

713

Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain

714

Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) Scaffold: Exploration of P1′ alkoxy residues and an aminoethylene (AE) central core Original Research Article

715

Discovery of potent cholecystokinin-2 receptor antagonists: Elucidation of key pharmacophore elements by X-ray crystallographic and NMR conformational analysis Original Research Article

716

Discovery of potent CRTh2 (DP2) receptor antagonists

717

Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain Original Research Article

718

Discovery of potent HIV-1 protease inhibitors incorporating sulfoximine functionality

719

Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability

720

Discovery of potent inhibitors of pseudomonal quorum sensing via pharmacophore modeling and in silico screening

721

Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents

722

Discovery of potent pyrrolidone-based HIV-1 protease inhibitors with enhanced drug-like properties

723

Discovery of potent sulfonamide P4-capped ketoamide second generation inhibitors of hepatitis C virus NS3 serine protease with favorable pharmacokinetic profiles in preclinical species Original Research Article

724

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain

725

Discovery of potent T-type calcium channel blocker

726

Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties

727

Discovery of potent, orally active benzimidazole glucagon receptor antagonists

728

Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stability Original Research Article

729

Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis

730

Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors

731

Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors

732

Discovery of Potential Natural Dipeptidyl Peptidase-4 Inhibitors for Type-2 Diabetes Treatment via Structure-Based Virtual Screening

733

Discovery of predictive rule sets for chlorophyll-a dynamics in the Nakdong River (Korea) by means of the hybrid evolutionary algorithm HEA

734

Discovery of probable Tunguska cosmic body material: anomalies of platinum group elements and rare-earth elements in peat near the Explosion Site (1908)

735

Discovery of Prognostic Signature Genes for Overall Survival Prediction in Gastric Cancer

736

Discovery of protein–protein binding disruptors using multi-component condensations small molecules

737

Discovery of proteins related to coronary artery disease using industrial-scale proteomics analysis of pooled plasma

738

Discovery of Pseudofrenelopsis from the Lower Cretaceous of Liupanshan Basin and its paleoclimatic significance

739

Discovery of pyrazine carboxamide CB1 antagonists: The introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series

740

Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A

741

Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor Original Research Article

742

Discovery of pyrimidine benzimidazoles as Lck inhibitors: Part I

743

Discovery of pyrrole-based hepatoselective ligands as potent inhibitors of HMG-CoA reductase Original Research Article

744

Discovery of quinazolines as a novel structural class of potent inhibitors of NF-κB activation Original Research Article

745

Discovery of radiolaria and conodonts in the Carboniferous–Permian of San Salvador Patlanoaya (Puebla, Mexico); biostratigraphic implications

746

Discovery of radiolaria from Upper Cretaceous Oceanic Red Beds in Daba, Kangmar and its paleogeographic implication

747

Discovery of recurrent multiple brain states in non-convulsive status epilepticus

748

Discovery of Ro 48-5695: A potent mixed endothelin receptor antagonist optimized from bosentan

749

Discovery of rubidium, strontium, molybdenum, and rhodium isotopes

750

Discovery of safety biomarkers for atorvastatin in rat urine using mass spectrometry based metabolomics combined with global and targeted approach Original Research Article

751

Discovery of samarium, europium, gadolinium, and terbium isotopes

752

Discovery of sapphirine-bearing Mg–Al granulites in the North China Craton: Implications for Paleoproterozoic ultrahigh temperature metamorphism

753

Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development

754

Discovery of scandium, titanium, mercury, and einsteinium isotopes

755

Discovery of selective aldo-keto reductase ligands—an on-bead assay strategy

756

Discovery of selective and nonpeptidic cathepsin S inhibitors

757

Discovery of selective dopamine D3 ligands: I. Dimeric 2-[4-(3-aminopropoxy)phenyl]benzimidazole antagonists

758

Discovery of selective dopamine D3 ligands: II. 2-[4-[3-(4-aryl-1-piperazinyl)propoxy]phenyl]benzimidazole partial agonists

759

Discovery of selective dopamine D4 receptor antagonists: 1-Aryloxy-3-(4-aryloxypiperidinyl)-2-propanols

760

Discovery of selective hydroxamic acid inhibitors of tumor necrosis factor-α converting enzyme

761

Discovery of selective imidazole-based inhibitors of mammalian 15-lipoxygenase: Highly potent against human enzyme within a cellular environment

762

Discovery of selective metal-binding peptoids using 19F encoded combinatorial libraries

763

Discovery of selective phosphonamide-based inhibitors of tumor necrosis factor-α converting enzyme (TACE)

764

Discovery of selective, small-molecule inhibitors of RNA complexes—1. The tat protein/TAR RNA complexes required for HIV-1 transcription Original Research Article

765

Discovery of selective, small-molecule inhibitors of RNA complexes—II. Self-splicing group I intron ribozyme Original Research Article

766

Discovery of small molecule agonists for the bombesin receptor subtype 3 (BRS-3) based on an omeprazole lead

767

Discovery of small molecule antagonists of TRPV1

768

Discovery of small molecule benzimidazole antagonists of the chemokine receptor CXCR3

769

Discovery of small molecule inhibitors of integrin αvβ3 through structure-based virtual screening

770

Discovery of small-molecule inhibitors of tyrosinase

771

Discovery of soluble epoxide hydrolase inhibitors from natural products

772

Discovery of Specific Inhibitors of Human USP7/HAUSP Deubiquitinating Enzyme Original Research Article

773

Discovery of substituted 3,4-Diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol

774

Discovery of substituted 8,9-dicarboxyldibenzo [2,3:5,6] bicyclo [5.2.0] nonan-4-ones with moderate binding affinity to the endothelin ETA and ETB receptors

775

Discovery of subtle effects in a human intervention trial through multilevel modeling

776

Discovery of subtype-selective NMDA receptor ligands: 4-Benzyl-1-piperidinylalkynylpyrroles, pyrazoles and imidazoles as NR1 /2B antagonists

777

Discovery of sulfonylalkylamides: A new class of orally active factor Xa inhibitors Original Research Article

778

Discovery of superoxide reductase: an historical perspective

779

Discovery of symmetry by voting method

780

Discovery of tantalum, rhenium, osmium, and iridium isotopes

781

Discovery of tertiary aminoacids as dual PPARα/γ agonists-I

782

Discovery of tetrahydro-β-carbolines as inhibitors of the mitotic kinesin KSP Original Research Article

783

Discovery of tetralin ureas as potent melanin concentrating hormone 1 receptor antagonists

784

Discovery of the arsenic isotopes

785

Discovery of the astatine, radon, francium, and radium isotopes

786

Discovery of the barium isotopes

787

Discovery of the bi-layered structure in spin-coated polyacrylamide films on the gold surface

788

Discovery of the cadmium isotopes

789

Discovery of the calcium, indium, tin, and platinum isotopes

790

Discovery of the catechol structural moiety as a Stat3 SH2 domain inhibitor by virtual screening

791

Discovery of the cerium isotopes

792

Discovery of the cobalt isotopes

793

Discovery of the connection among age-related macular degeneration, MTHFR C677T and PAI 1 4G/5G gene polymorphisms, and body mass index by means of Bayesian inference methods

794

Discovery of the content of rumination thoughts among women with marital conflicts: Qualitative study

795

Discovery of the cross-coupling reaction between Grignard reagents and C(sp2) halides catalyzed by nickel–phosphine complexes

796

Discovery of the Endocannabinoid System: A Breakthrough in Neuroscience

797

Discovery of the Eucalyptus canker pathogen Chrysoporthe cubensis on native Miconia (Melastomataceae) in Colombia

798

Discovery of the first antibacterial small molecule inhibitors of MurB

799

Discovery of the first non-planar flavonoid that can strongly inhibit xanthine oxidase: protoapigenone 1′-O-propargyl ether

800

Discovery of the first Quaternary maar in the Bohemian Massif, Central Europe, based on combined geophysical and geological surveys

801

Discovery of the first series of inhibitors of human papillomavirus type 11: inhibition of the assembly of the E1–E2–Origin DNA complex

802

Discovery of the genera Bolothrips Priesner, 1926 and Cephalothrips Uzel, 1895 (Thysanoptera: Phlaeothripidae) from the Oriental region

803

Discovery of the genus Cinetus Jurine, 1807 (Hymenoptera: Diapriidae) from Iran, with five species records

804

Discovery of the gold isotopes

805

Discovery of the hypothalamic gonadotropin-releasing hormone pulse generator and of its physiologic significance

806

Discovery of the iron isotopes

807

Discovery of the Isotopes with 11≤Z≤19

808

Discovery of the krypton isotopes

809

Discovery of the largest impact crater field on Earth in the Gilf Kebir region, Egypt

810

Discovery of the Life-Organizing Principle: In Search of the Fundamentals Laws of Life, E.M. Elsheik. iUniverse LLC, Bloomington, USA (2014)

811

Discovery of the Life-Organizing Principle: In Search of the Fundamentals Laws of Life, E.M. Elsheik. iUniverse LLC, Bloomington, USA (2014)

812

Discovery of the Low-Redshift Optical Afterglow of GRB 011121 and Its Progenitor Supernova SN 2001ke

813

Discovery of the male of the subterranean species niphargus ozimeci karaman, g., 2011 (fam. niphargidae) in bosnia Herzegovina (contribution to the knowledge of the amphipoda 262)

814

Discovery of the male of the subterranean species niphargus ozimeci karaman, g., 2011 (fam. niphargidae) in bosnia & Herzegovina (contribution to the knowledge of the amphipoda 262)

815

Discovery of the most rapidly-rotating, non-degenerate, magnetic massive star by the MiMeS collaboration

816

Discovery of the new proton emitter 144Tm

817

Discovery of the New Target for Identification of Mycobacterium tuberculosis

818

Discovery of the Ordovician Millbrig K-bentonite Bed in the Trenton Group of New York State: implications for regional correlation and sequence stratigraphy in eastern North America

819

Discovery of the Oriental genus Piyumoides Leclercq, 1963 (Hymenoptera, Crabronidae) in the Indian subcontinent with the description of a new species

820

Discovery of the Paleo-Tethys residual peridotites along the Anyemaqen–KunLun suture zone (North Tibet)

821

Discovery of the predatory mite Neoseiulus californicus (Acari: Phytoseiidae) in some rose greenhouses in Iran and describing variation in spermathecal calyx shape

822

Discovery of the rotational spectrum of the weakly bound complex CO–H2

823

Discovery of the silver isotopes

824

Discovery of the thallium, lead, bismuth, and polonium isotopes

825

Discovery of the tungsten carbonyl-catalyzed endo-selective alkynyl alcohol cycloisomerization reaction: applications to stereoselective syntheses of d-olivose, d-olivose disaccharide substructures of landomycin and mithramycin

826

Discovery of the tungsten isotopes

827

Discovery of the vanadium isotopes

828

Discovery of the Yamato Meteorites in 1969

829

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: Design, synthesis and structure–activity relationship studies

830

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: Metabolism-directed optimization studies towards orally bioavailable derivatives

831

Discovery of thieno[2,3-c]pyridines as potent COT inhibitors

832

Discovery of thienopyridines as Src-family selective Lck inhibitors

833

Discovery of Thioazepinone Ligands for Src SH2: From Non-specific to Specific Binding

834

Discovery of thiochroman and chroman derivatives as pure antiestrogens and their structure–activity relationship Original Research Article

835

Discovery of thiochroman derivatives bearing a carboxy-containing side chain as orally active pure antiestrogens

836

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides

837

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: Tertiary amides

838

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: Tertiary amides

839

Discovery of three new mordellids (Coleoptera, Tenebrionoidea) from the Yixian Formation of western Liaoning, China

840

Discovery of TNF Inhibitors from a DNA-Encoded Chemical Library based on Diels-Alder Cycloaddition Original Research Article

841

Discovery of trans-3,4′-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation

842

Discovery of trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1′-cyclohexane]-4′-carboxamide, a potent and orally active neuropeptide Y Y5 receptor antagonist Original Research Article

843

Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase

844

Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB

845

Discovery of two northern hemisphere Armillaria species on Proteaceae in South Africa

846

Discovery of two ophiolite complexes of different ages in the Khoy area (NW Iran)

847

Discovery of two potential DAZL gene markers for sperm quality in boars by population association studies

848

DISCOVERY OF ULTRACOMPACT DWARF GALAXIES IN THE VIRGO CLUSTER

849

Discovery of underground argon with low level of radioactive 39Ar and possible applications to WIMP dark matter detectors

850

Discovery of underground argon with low level of radioactive 39Ar and possible applications to WIMP dark matter detectors

851

Discovery of Unertan Syndrome and Reverse Evolution: As An “Aha!” Experience

852

Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans

853

Discovery of Wall Teichoic Acid Inhibitors as Potential Anti-MRSA β-Lactam Combination Agents Original Research Article

854

Discovery of whitlockite in mantle xenoliths: Inferences for water- and halogen-poor fluids and trace element residence in the terrestrial upper mantle

855

Discovery of Widespread GTP-Binding Motifs in Genomic DNA and RNA Original Research Article

856

Discovery of X-Ray Burst Oscillations from a Neutron Star X-Ray Transient in the Globular Cluster NGC 6440

857

Discovery of X-Ray Quasi-Periodic Oscillations from an Ultraluminous X-Ray Source in M82: Evidence against Beaming

858

Discovery of yttrium, zirconium, niobium, technetium, and ruthenium isotopes

859

Discovery of zinc, selenium, bromine, and neodymium isotopes

860

Discovery of zoniporide: A potent and selective sodium–hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility

861

Discovery of β-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors

862

Discovery of γ-secretase inhibitors efficacious in a transgenic animal model of Alzheimer’s disease

863

Discovery potential for doubly charged Higgs bosons in e+e− collisions at LEP

864

Discovery potential for new physics in view of the RHIC-Spin upgrade

865

Discovery potential of new boson image in the Minimal Higgsless model at LHC Original Research Article

866

Discovery prospects for a supernova signature of biogenic origin

867

Discovery stage pharmacokinetics using dried blood spots

868

Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay Original Research Article

869

Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator

870

Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)

871

Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors

872

Discovery, SAR, synthesis, pharmacokinetic and biochemical characterization of A-192411: A novel fungicidal lipopeptide-(I)

873

Discovery, structure and biological activities of cyclotides

874

Discovery, structure and HIV-1 integrase inhibitory activities of integracins, novel dimeric alkyl aromatics from Cytonaema sp.

875

Discovery, structure–activity relationship study, and oral analgesic efficacy of cyproheptadine derivatives possessing N-type calcium channel inhibitory activity Original Research Article

876

Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1) Original Research Article

877

Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2) Original Research Article

878

Discovery, synthesis and biological evaluation of novel glucokinase activators

879

Discovery, synthesis, and structure–activity studies of tetrazole based growth hormone secretagogues

880

Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure–activity relationships of 2-methoxystypandrone and its analogues

881

Discovery, visualization and performance analysis of enterprise workflow

882

Discrepancies among clinical, histological and immunological findings in IgA pemphigus: a case report and literature survey

883

Discrepancies Between Biopsy Gleason Score and Radical Prostatectomy Specimen Gleason Score: An Iranian Experience

884

Discrepancies between catheter and Doppler estimates of valve effective orifice area can be predicted from the pressure recovery phenomenon: practical implications with regard to quantification of aortic stenosis severity

885

Discrepancies between classic anatomy and modern gynecologic surgery on pelvic connective tissue structure: Harmonization of those concepts by collaborative cadaver dissection

886

Discrepancies between desired and perceived measures of performance of IS professionals: Views of the IS professionals themselves and the users

887

Discrepancies between desired and perceived measures of performance of IS professionals: Views of the IS professionals themselves and the users

888

Discrepancies between echocardiographic measurements of left ventricular mass in a healthy adult population

889

Discrepancies between ecological and individual data on fruit and vegetable consumption in fifteen countries

890

Discrepancies between ergosterol and the phospholipid fatty acid 18:2ω6,9 as biomarkers for fungi in boreal forest soils

891

Discrepancies between ergosterol and the phospholipid fatty acid 18:2ω6,9 as biomarkers for fungi in boreal forest soils

892

Discrepancies Between Free Vibration of FML and Composite Cylindrical Shells Reinforced by CNTs

893

Discrepancies between metric dimension and partition dimension of a connected graph Original Research Article

894

Discrepancies between microscopic (TEM) and macroscopic (texture) observations in high temperature deformation of FeAl and Fe3Al-based alloys

895

Discrepancies between microscopic (TEM) and macroscopic (texture) observations in high temperature deformation of FeAl and Fe3Al-based alloys

896

Discrepancies between N-Acetyl Cysteine Prescription based on Patient’s History and Plasma Acetaminophen Level

897

Discrepancies Between Normative and Descriptive Models of Decision Making and the Understanding/Acceptance Principle,

898

Discrepancies between roughness measurements obtained with phase-shifting and white-light interferometry

899

Discrepancies between Self- and Clinical Staff Members’ Perception of Cognitive Functioning among Patients with Schizophrenia Undergoing Long-Term Hospitalization

900

Discrepancies between self and observer ratings of depression: The relationship to demographic, clinical and personality variables

901

Discrepancies between self-report and objective measures for stimulant drug use in HIV: Cognitive, medication adherence and psychological correlates

902

Discrepancies between self-reported and observed physical function in the elderly: the influence of response shift and other factors

903

Discrepancies between self-reported years of education and estimated reading level among elderly community-dwelling African-Americans: Analysis of the MOAANS data

904

Discrepancies Between Sizer and Valve Dimensions: Implications for Small Aortic Root

905

Discrepancies between the Speech of Male and Female in Lecturing: Language Management in Focus

906

Discrepancies in brine density databases at geothermal conditions

907

Discrepancies in Cancer Mortality Estimates

908

Discrepancies in diagnosing Osteopenia and Osteoporosis with bone densitometry at spine and femoral neck

909

Discrepancies in earthquake location between ISC and other agencies

910

Discrepancies in Evaluating Farm Management Routines as Risk Factors of Raw Milk and Udder Hygiene in Selected Dairy Farms of Fars Province, Iran

911

Discrepancies in initial death certificate diagnoses in sudden unexpected out-of-hospital deaths: the role of cardiovascular autopsy

912

Discrepancies in interpretation of ED body computed tomographic scans by radiology residents

913

Discrepancies in interpretation of night-time emergency computed tomography scans by radiology residents

914

Discrepancies in mental functioning relative to word knowledge on the Speed and Capacity of Language-Processing Test

915

Discrepancies in military middle-school adolescentsʹ and parentsʹ perceptions of family functioning, social support, anger frequency, and concerns

916

Discrepancies in pelvic anatomy

917

Discrepancies in performance status scores as determined by cancer patients and oncologists: are they influenced by depression?

918

Discrepancies in SART (Society for Assisted Reproductive Technology) reporting

919

Discrepancies in the Monte Carlo simulations of propagation of ultra-high energy cosmic-ray photons in the geomagnetic field

920

Discrepancies in the morphology and physical properties of amorphous and crystalline sprayed lanthanum nickel oxide films Original Research Article

921

Discrepancy and signed domination in graphs and hypergraphs

922

Discrepancy behaviour in the non-asymptotic regime Original Research Article

923

Discrepancy between actual and ideal body images: Impact on eating and exercise behaviors

924

Discrepancy between Actual and Theoretical Anterior Chamber Depth in Patients with Morcher Posterior Chamber Intraocular Lens

925

Discrepancy between Admission and Discharge Diagnoses in Central Serbia: Analysis by the Groups of International Classification of Diseases, 10th Revision

926

Discrepancy Between Admission Diagnosis and Discharge Diagnosis in Cardiovascular Diseases: An Analysis Based On the Groups of International Classification Disease, 10th Revision

927

Discrepancy between auditory brainstem responses, auditory steady-state responses, and auditory behavior in two patients with Pelizaeus-Merzbacher disease

928

Discrepancy between clinical staging through bimanual palpation and pathological staging after cystectomy

929

Discrepancy between fatigue and dwell-fatigue behavior of near alpha titanium alloys simulated by cellular automata

930

Discrepancy Between Intraoperative Transesophageal Echocardiography and Postoperative Transthoracic Echocardiography in Assessing Congenital Valve Surgery

931

Discrepancy between photoluminescence and photoresponse intensities in n-InAs/GaAs and InAs/n-GaAs quantum-dot heterostructures

932

Discrepancy between second and first opinion in surgical oncological patients

933

Discrepancy between serum leptin values and total body fat in response to the oral growth hormone secretagogue MK-677

934

Discrepancy between Sr isotope and biostratigraphic datings of the upper middle and upper Miocene successions (Eastern North Sea Basin, Denmark)

935

Discrepancy between subjective and objective ratings for negative symptoms

936

Discrepancy between the theory and polarization observations in the 530.3 nm solar coronal line Original Research Article

937

Discrepancy between theory and real computation on the stability of some finite element schemes

938

Discrepancy detection and developmental changes in attentional engagement in infancy

939

Discrepancy estimates based on Haar functions Original Research Article

940

Discrepancy for uniform design of experiments with mixtures

941

Discrepancy in ABO Blood Grouping in a Blood Donor: A Case Report

942

Discrepancy in different numbers of colors Original Research Article

943

Discrepancy in generalized arithmetic progressions

944

Discrepancy in pd breakup reaction at image Original Research Article

945

Discrepancy in regression estimates between log-normal and gamma: some case studies

946

Discrepancy in Screening Performances of Different Rapid Test Kits for SARS-CoV-2; a Letter to Editor

947

Discrepancy in serum carcinoembryonic antigen levels by measuring kits

948

Discrepancy in serum carcinoembryonic antigen levels by measuring kits: Reply

949

Discrepancy in the preferences of place of death between terminally ill cancer patients and their primary family caregivers in Taiwan

950

Discrepancy measures for selecting optimal combination of parameter values in object-based image analysis

951

Discrepancy of (centered) arithmetic progressions in

952

Discrepancy of Arithmetic Progressions in Higher Dimensions Original Research Article

953

Discrepancy of Centered Arithmetic Progressions in (Extended Abstract)

954

Discrepancy of computed tomographic image between lung and mediastinal windows as a prognostic implication in small lung adenocarcinoma

955

Discrepancy of Graham Greene

956

Discrepancy of response of hPTH administration and its withdrawal between trabecular and cortical bone sites in ovx rats

957

Discrepancy of structural stability against temperature between metallic liquids and their glasses

958

Discrepancy of Sums of Arithmetic Progressions

959

Discrepancy of Sums of two Arithmetic Progressions

960

Discrepancy of the spectral data between adunctin E and the synthetic one

961

Discrepancy of Weyl Sequences (nα) Perturbed by Rationally Periodic Functions

962

Discrepancy principle for DSM II

963

Discrepancy principle for the dynamical systems method

964

Discrepancy rates of preliminary and final reports for after-hours pediatric teleradiology interpretations

965

Discrepancy searchfortheflexiblejobshopschedulingproblem

966

Discrepancy with respect to convex polygons

967

Discrepancy-based error estimates for Quasi-Monte Carlo I. General formalism Original Research Article

968

Discrepancy-based error estimates for Quasi-Monte Carlo II. Results in one dimension Original Research Article

969

Discrepancy-based error estimates for Quasi-Monte Carlo III. Error distributions and central limits Original Research Article

970

Discrepant analysis and screening for Chlamydia trachomatis

971

Discrepant analysis and screening for Chlamydia trachomatis

972

Discrepant analysis and screening for Chlamydia trachomatis

973

Discrepant analysis and screening for Chlamydia trachomatis

974

Discrepant analysis and screening for Chlamydia trachomatis

975

Discrepant analysis and screening for Chlamydia trachomatis

976

Discrepant analysis—or behaviour?

977

Discrepant and congruent high self-esteem: Behavioral self-handicapping as a preemptive defensive strategy

978

Discrepant Cytogenetic and Fluorescence In Situ Hybridization Results in a 26-Year-Old Male with Early T-Cell Acute Lymphocytic Leukemia

979

Discrepant epidemiological patterns between classical and atypical scrapie in sheep flocks under French TSE control measures

980

Discrepant fluency increases subjective truth

981

Discrepant illness perceptions, affect and expressed emotion in people with psychosis and their carers

982

Discrepant impacts of land use and land cover on urban heat islands: A case study of Shanghai, China

983

Discrepin, a new peptide of the sub-family α-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+-channels (IA currents) of cerebellum granular cells

984

Discrete (carbon free) chelate rings derived from sodium tetraphenylimidodiphosphinochalcogenides (S and Se) and 15-crown-5

985

Discrete 3D model as complimentary numerical testing for anisotropic damage

986

Discrete abstractions for robot motion planning and control in polygonal environments

987

Discrete accidental symmetry for a particle in a constant magnetic field on a torus Original Research Article

988

Discrete acoustic emission waves during stick–slip friction between steel samples

989

Discrete actions on nilpotent Lie groups and negatively curved spaces

990

Discrete active models and applications

991

Discrete Adaptive Sliding Mode Control of a State-Space System with a Bounded Disturbance

992

Discrete adaptive sliding-mode control of a class of stochastic systems

993

Discrete adaptive sliding-mode tracking controller

994

Discrete ADM: A tool for solving a class of classic and fractional difference problems

995

Discrete Adomian Decomposition solution of Nonlinear Fredholm Integral Equation

996

Discrete algebraic estimator design for non-linear Liouvillian systems with sampled output: Application to a class of stirred bioreactor

997

Discrete analog electronics for high-resistivity silicon detectors used for X-ray and γ-ray spectroscopy in whole-body monitoring

998

Discrete analog electronics for high-resistivity silicon detectors used for X-ray and γ-ray spectroscopy in whole-body monitoring

999

Discrete analogue of Fučik spectrum of the Laplacian

1000

Discrete anchoring: Bulk-substrate coupling in lattice models